Special delivery: targeted therapy with small RNAs

Introduction: Antibody-targeted therapy special issue.

Lean: Targeted Therapy for Care Delivery.

Advances in cancer care have reached unprecedented milestones, but these achievements come at significantly high costs.1 Disorganized and uncoordinated care can harm patients and contributes to unsustainable expenses. The CMS Innovation Center is addressing these issues with financial incentives under the Oncology Care Model (OCM) umbrella that aims to provide higher quality and more coordinate...

Advances in Targeted Drug Delivery

Advances in Targeted Drug Delivery

Non-Viral Delivery and Therapeutic Application of Small Interfering RNAs

RNA interference (RNAi) is a powerful method used for gene expression regulation. The increasing knowledge about the molecular mechanism of this phenomenon creates new avenues for the application of the RNAi technology in the treatment of various human diseases. However, delivery of RNA interference mediators, small interfering RNAs (siRNAs), to target cells is a major hurdle. Effective and saf...